[phyrrus9]

You may want to go down to 4x8gb's.. smaller sizes are less dense and tend to perform better under load. DDR4 has ECC, but if you're constantly correcting effective row hammers, you're losing speed

Good point, but that'll leave me with 32GB In total. I have that capacity now and I'm planning to double It with 4x16GB.

Surely the loss of speed wouldn't constitute to the equivalent of 16GB usable/available memory @2400MHz?

No, it won't make any difference in capacity, but a massive difference in usability and durability. That's a similar reason it's more efficient to have an array of small drives rather than one large drive.