+- Sinisterly (https://sinister.ly)
+-- Forum: General (https://sinister.ly/Forum-General)
+--- Forum: World News (https://sinister.ly/Forum-World-News)
+--- Thread: Pfizer / AZ Effective Against Indian Variant (/Thread-Pfizer-AZ-Effective-Against-Indian-Variant)
Pages:
1
2
Pfizer / AZ Effective Against Indian Variant - Jiggly - 05-23-2021
I'm sure many of us are tired of reading about Covid-19 and vaccines. However, I thought this was interesting. A study was conducted between 5th April and 16th May 2021, in the UK, to investigate how effective the Pfizer, AstraZeneca (AZ) and Moderna vaccines are against the Indian variant, known as B.1.617.2, compared also to their effectiveness against the Kent variant (the UK variant). Unfortunately, the UK did not have enough Moderna vaccines at the time of the study, so data for Moderna was not included.
There is a statistically significant difference between the Pfizer and AZ vaccines, which could be attributed to the Pfizer jab being given to more young people as it was the first rolled-out to front line workers. The AZ vaccine initial rollout targeted the elderly/older age groups. In short: The sample for the study could explain that difference.
The study also highlighted the astonishing difference in effectiveness between first and second doses. I think they're hoping to encourage people to get their second dose. Information on the second dose said that the first dose does offer a chunk of protection, but around 60% (or less) and it's effectiveness wears off much more quickly.
You can see the full publication for this study here.
Code:
Two jabs of either vaccine give a similar level of protection against symptomatic disease from the Indian variant as they do for the Kent one.
However, both vaccines were only 33% effective against the Indian variant three weeks after the first dose.
This compared with 50% effectiveness against the Kent variant.
Public Health England, which ran the study, said the vaccines are likely to be even more effective at preventing hospital admission and deaths.
______________________________________
The Pfizer vaccine was found to be 88% effective at stopping symptomatic disease from the Indian variant two weeks after the second dose, compared with 93% effectiveness against the Kent variant.
The AstraZeneca jab was 60% effective against the Indian variant, compared with 66% against the Kent variant.
Public Health England (PHE) said the difference in effectiveness between the vaccines after two doses might be explained by the fact that rollout of second doses of AstraZeneca was later than for the Pfizer vaccine, which was approved first.
Other data shows it takes longer to reach maximum effectiveness with the AstraZeneca vaccine, PHE said.
Some 12,675 genome-sequenced cases were included in the study, which took place between 5 April and 16 May. Only 1,054 of those cases were of the Indian variant, known as B.1.617.2.Source
RE: Pfizer / AZ Effective Against Indian Variant - Skullmeat - 05-23-2021
Im not surprised. Its likely that the covid vaccine will end up being like our seasonal flu shot, which is often tweaked to target new variations of the flu virus as well.
RE: Pfizer / AZ Effective Against Indian Variant - Oni - 05-24-2021
(05-23-2021, 05:14 PM)Skullmeat Wrote: Im not surprised. Its likely that the covid vaccine will end up being like our seasonal flu shot, which is often tweaked to target new variations of the flu virus as well.
A 3rd or 4th might kill me.
RE: Pfizer / AZ Effective Against Indian Variant - mothered - 05-24-2021
(05-24-2021, 01:52 AM)Oni Wrote: A 3rd or 4th might kill me.The first shot may also do the same.
https://www.straitstimes.com/asia/vietnam-reports-first-death-in-patient-who-received-astrazeneca-covid-19-vaccine
RE: Pfizer / AZ Effective Against Indian Variant - ConcernedCitizen - 05-24-2021
I mean, yes, any vaccine can do this. Measles, Tetanus; both are very well-known and required by schools before enrolling children. But the rate of success is very high and it's extremely rare to get a vaccine which subsequently kills you. That said, I would rather not catch the whooping cough or tetanus. I get cuts and bruises all the time and to die from a pin prick, I'd be pretty mad. But I'd be dead.
![[Image: tetanus-chart-1947-2018.png]](https://cdc.gov/tetanus/images/tetanus-chart-1947-2018.png)
Reported tetanus cases have declined more than 95%, and deaths from tetanus have declined more than 99% in the United States since 1947. Sporadic cases of tetanus continue to occur in adults who did not get all the recommended tetanus vaccinations. This includes people who have never received a tetanus vaccine or adults who don’t stay up to date on their 10-year booster shots.
Fuck vaccines, though, right? BTFO science.
RE: Pfizer / AZ Effective Against Indian Variant - Jiggly - 05-24-2021
(05-24-2021, 06:14 AM)vittring Wrote: I mean, yes, any vaccine can do this. Measles, Tetanus; both are very well-known and required by schools before enrolling children. But the rate of success is very high and it's extremely rare to get a vaccine which subsequently kills you. That said, I would rather not catch the whooping cough or tetanus. I get cuts and bruises all the time and to die from a pin prick, I'd be pretty mad. But I'd be dead.
Reported tetanus cases have declined more than 95%, and deaths from tetanus have declined more than 99% in the United States since 1947. Sporadic cases of tetanus continue to occur in adults who did not get all the recommended tetanus vaccinations. This includes people who have never received a tetanus vaccine or adults who don’t stay up to date on their 10-year booster shots.
Fuck vaccines, though, right? BTFO science.
While I totally agree with you, to Oni's defense, he's not an anti-vaxxer. He was legitimately the most ill he's ever been after his second dose of Pfizer. So I understand why he feels that way.
I personally would still vastly prefer having the vaccine over the real disease. I'm not convinced I'd survive the real thing.
RE: Pfizer / AZ Effective Against Indian Variant - ConcernedCitizen - 05-25-2021
(05-24-2021, 03:25 PM)Jiggly Wrote: While I totally agree with you, to Oni's defense, he's not an anti-vaxxer. He was legitimately the most ill he's ever been after his second dose of Pfizer. So I understand why he feels that way.I had COVID for 3 weeks and still have yet to get my "free" vaccine. There's not only a waiting list, but also a lot of preferential treatment going on where I live. I wouldn't wish that on anybody. It was the worst because I am a former smoker, and I have never experienced coughing like that, or struggling to breath at night.
I personally would still vastly prefer having the vaccine over the real disease. I'm not convinced I'd survive the real thing.
RE: Pfizer / AZ Effective Against Indian Variant - Jiggly - 05-25-2021
(05-25-2021, 05:46 AM)vittring Wrote:(05-24-2021, 03:25 PM)Jiggly Wrote: While I totally agree with you, to Oni's defense, he's not an anti-vaxxer. He was legitimately the most ill he's ever been after his second dose of Pfizer. So I understand why he feels that way.I had COVID for 3 weeks and still have yet to get my "free" vaccine. There's not only a waiting list, but also a lot of preferential treatment going on where I live. I wouldn't wish that on anybody. It was the worst because I am a former smoker, and I have never experienced coughing like that, or struggling to breath at night.
I personally would still vastly prefer having the vaccine over the real disease. I'm not convinced I'd survive the real thing.
Have you made a full recovery now? Sorry to hear you went through that.
I'm aware my elderly family who had gotten and survived covid, got their jabs a little later on, as they would have still had antibodies, but otherwise ours has gone through priorities of Frontline workers/elderly, then most clinically vulnerable, then down through the age groups, with the youngest folk last (therefore the least at risk group last). I think we're down to over 30s/any medical conditions are able to just go get the jab now.
RE: Pfizer / AZ Effective Against Indian Variant - ConcernedCitizen - 05-25-2021
(05-25-2021, 12:10 PM)Jiggly Wrote: Have you made a full recovery now?Yeah, I felt fine after some rest and a [paid] period of vacation from work.
I believe that's what they are doing now - front line, then elderly and then middle-aged and so forth.
I'm in the 30+ block (and I already had the virus) so I'm not a huge priority.
RE: Pfizer / AZ Effective Against Indian Variant - Jiggly - 05-25-2021
(05-25-2021, 12:47 PM)vittring Wrote:(05-25-2021, 12:10 PM)Jiggly Wrote: Have you made a full recovery now?Yeah, I felt fine after some rest and a [paid] period of vacation from work.
I believe that's what they are doing now - front line, then elderly and then middle-aged and so forth.
I'm in the 30+ block (and I already had the virus) so I'm not a huge priority.
Hope you get yours soon. How's the rollout been where you are? Is it slow or?